Dr. Shafiullah Khan
Assistant Professor of Chemistry
Department of Chemistry Gomal University, D.I.Khan K.P.K, Pakistan.
Email: s.khan@gu.edu.pk
Email: s.khan@mail.buct.edu.cn
Ph: (Office) (+92-966) 750359
Cell: (+92-321) 2327453
Personal Information
Date of Birth: 16-08-1981
Marital Status: Married
Nationality: Pakistani
N.I.C #: 11201-1902982-5
Passport No: HX4109821
Education
Year Degree
2013-15 Postdoc (CAEM, Beijing University of Chemical Technology, China.
2009 Ph.D (Organic & Bio-Organic Chemistry)
2003 M.Sc (Organic Chemistry)
2001 B.Sc
1999 F.Sc
1997 S.S.C
Achievement
Year Achievement
2004 Indigenous 5000 fellowship of Higher Education Commission of Pakistan.
2006 International Researc Support Initiative Program (IRSIP) Scholarship, Awarded by Higher Education Commission of Pakistan.
2009 Assistant Professor, Department of Chemistry, University of Science & Technology, Bannu, Pakistan.
2010 up to
now Assistant Professor, Institute of Chemical Scineces, Gomal University, D.I.Khan, Pakistan.
Language
Skills Language Written Spoken
English Excellent Excellent
Urdu Excellent Excellent
Ph. D Title
Phytochemical investigations on constituent of cotoneaster racemiflora Desf & Buddleja crispa Benth along with the synthesis of macrocyclic β-sheet peptides.
Research Experience
2005-2008 Fully conversant working experience with the following instruments:
NMR
Recycling HPLC (LC 908W) and Chiral HPLC FT IR and UV Spectrophotometers
LC-MS
Peptide synthesizer
2005-2009 I have worked on “Un natural synthesis of amino acid, “Divalent Tau Peptide” for Alzheimer’s disease at University of California, Irvine, U.S.A. One research paper is published in “Journal of American Chemical Society”. I have also experience on bio assay guided natural product has been isolated through different separation techniques. I have experience in Column Chromatography; flash Chromatography, Recycling/ preparative HPLC, MPLC and LC-NMR. After purification the compounds are subjected to physical organic techniques for structural elucidation. I have the ability to interpret
1HNMR, 13CNMR, DEPT experiments. We routinely performed 2D NMR technique such COSY, NOESY, HMQC and HMBC etc. More over I have a full command over the interpretation of different Mass Techniques including E.I and HR, FAB (+ve) & FAB (-ve). I am also familiar with UV, IR, Spectroscopic methods. Recently I am working on Bio-based elastomer synthesis in the college of material science, Beijing University of Chemical Technology, China.
2013-2015 Postdoc (CAEM), Beijing University of Chemical Technology, Beijing, China.
International .Course on X-Ray Crystallography by Dr. Masood Parveez of Calgary University Canada.
Training .Worked on “Un natural synthesis of amino acid, “Tau peptide” that inhibit the aggregation of Alzheimer’s disease, at University of California, Irvine, U.S.A.
Courses, .Course on “NMR Concept” by Dr. Daniel D. Traficant of Rhode University, Island.
Seminars .Recently, I am working on Bio-based elastomer synthesis in the college of material science, Beijing University of Chemical Technology, China
& Workshops
National
-
10th International symposium on Natural Product Chemistry (Jan.2006), held at HEJ Research Institute of Chemistry, University of Karachi, Pakistan.
Research Supervision
My research group included on 4 M.Phil and 4 PhD students. They are working on Green synthesis of silver and gold nanoparticles using medicinal plants and bio-guided natural product isolation and synthesis. Recently, two of my graduate students was got their Ph.D degree.
Editor
1. Editor of American Journal of Chemistry and Application
2. Editor of American Journal of Pharmacy and Pharmacology
3. Editor of VFAST transactions on Organic Chemistry
4. Editor of Universal Journal of Chemistry
5. Editor of American Journal of Science and Technology
BOOK
“Concept of Natural Product Chemistry” Shafiullah Khan, Lambert Academic Publishing, Saarbrücken, Germany (2012).
PUBLICATION
1. Shafiullah Khan, Zhao Wang, Runguo Wang and Liqun Zhang*
Synthesis and Structure Design of New Bio-Based Elastomers via Thiol-ene-Click Reactions
Materials Science and Engineering C 67, pp: 554-560 (2016)
2. Kamran Tahir, Aftab Ahmad, Baoshan Li, Arif Ullah Khan, Sadia Nazir, Shafiullah Khan, Zia Ul Haq Khan, Shahab Ullah Khan
Preparation, characterization and an efficient photocatalytic activity of Au/TiO2 nanocomposite prepared by green deposition method
Materials Letters 178, pp: 56–59 (2016)
3. Aftab Ahmad, Yun Wei, Fatima Syed, Shafiullah Khan, Gul Majid Khan, Kamran Tahir, Arif Ullah Khan, Faheem Ullah Khan, Qiping Yuan*
Isatis tinctoria mediated synthesis of amphotericin B-bound silver nanoparticles with enhanced photoinduced antileishmanial activity: A novel green approach
Journal of Photochemistry & Photobiology, B: Biology 161, pp: 17-24 (2016)
4. Farmanullah Khan, Fatima Syed, Arshiya Iqbal, ZiaUlHaq Khan,Hamidullah, Shafiullah Khan*
Synthesis, Spectral Characterization and Antibacterial Study of a Schiff Base Metal Complexes Derived from 4-Bromo-N-[(E)-(5-chloro-2- hydroxyphenyl) methylidene]benzene- sulfonamide.
Asian Journal of Chemistry, 28 (8), 1658-1660 (2016)
5. Arif Ullah Khan, Qipeng Yuan, Yun We, Kamran Tahir, Aftab Ahmad, Shafiullah Khan, Sadia Nazir, Faheem Ullah Khan
Ultra-efficient photocatalytic deprivation of methylene blue and biological activities of biogenic silver nanoparticles.
Journal of Photochemistry & Photobiology, B: Biology 159, pp: 49–58 (2016)
6. Fatima Syed, M. Javid Asad, Khurshid Ali, Muhammad Gulfaraz, Aftab Ahmad, Zahid Khan, Muhammad Imran, Raheela Taj and Shafiullah Khan*
Optimization of Various Parameters for Maximum Production of Glucoamylaze by Neurospora sitophila.
Asian Journal of Chemistry, 28(3), pp: 669-674 (2016)
7. Farman Khan, Fatima Syed, Abdul Khabir, Abdul Rauf, Zia Ul Haq, Masood Afzal, Malik Amanullah, Ali Author Hussain, Shafiullah Khan* Isolation, Antioxidant and Anti-fungal activities of two newly reported compounds from Bergenia ciliata.
Asian Journal of Chemistry 28 (9), pp: 1917-1920 (2016)
8. Farman Khan, Muhammad Akram, Abdul Khabir, Abdul Rauf, Zia Ul Haq, Masood Afzal, Malik Amanullah, Zakir Khan, Shafiullah Khan* Synthesis, Characterization and antibacterial activities of some Schiff bases prepared from 3-hydroxy-2-nepthaldehde and Phenyl Methanamine derivatives
Asian Journal of Chemistry 28 (9), pp: 1925-1928 (2016)
9. Dilfaraz Khan, Shafiullah Khan, Azim Khan Khattak, Hazrat Ali, Syed Badshah
Antifungal and Phytotoxic activities of ethyl acetate soluble fraction and purified compound (Ethyl 3-hydroxy 5-methoxy 4-methylbenzoate) from Lonicera quinquelocularis
Asian Journal of Chemistry 28 (9), 2001-2003 (2016)
10. Kamran Tahir, Baoshan Li, Shafiullah Khan, Sadia Nazir, Ziaulhaq khan and Arifullah khan
Enhanced chemocatalytic reduction of aromatic nitro compounds by biosynthesized gold nanoparticles
Journal of Alloys and Compounds, 651, pp: 322-327 (2015)
11. Dilfaraz Khan, Shafiullah Khan*, Syed Badshaha, Hazrat Ali, Hamidullah, Zia Muhammad and Simon Woodward
New furocarbazole alkaloids from Lonicera quinquelocularis,
Natural Product Research, (2015)
12. Masood Afzal, Liqun Zhang, Russell J. Cox, Nawshad Muhammad and Shafiullah Khan*
Isolation of two new Mallotoates with antifungal and radical scavenging activities from Mallotus Phillipensis mull
Asian Journal of Chemistry, 27 (10), pp: 3891-3894 (2015)
13. Farmanullah Khan, Shafiullah Khan*, Ali Athar, Wasim Ahmed, Zia Ul Haq
Synthesis, Spectral characertization and antibacterial study of a Schiff Base Metal Complexes derived from N-[(E)-5-chloro-2-Hydroxyphenyl]- Methylidene-4- Nitrobenzenesulfonamide
American-Eurasian Journal of Agricultural & Environmental Sciences 15(2) pp: 216-219 (2015)
14. Abdul Samad, Muhammad Adeel, Dilfaraz Khan, Syed Badshah, Shafiullah Khan, Jane Hanrahan
Two new bioactive furoquinoline alkaloids from zanthoxylum
Asian Journal of Chemistry, 27 (7) pp: 2468-2472 (2015)
15. Zia Ul Haq Khan, Arifullah Khan, Yongmei Chen, Shafiullah Khan, Pingyu wan and Xin Jin
Electrochemical oxidation of catechols in the presence of 4-mercapto-benzoic acid, to synthesis sulfanyl compounds and their biological studies
Tetrahedron, 71, pp: 1674-1678 (2015)
16. Farman Khan, Syed Badshah, Wang Zhao, Runguo Wang and Shafiullah Khan*
Isolation and antimicrobial efficacy tests of Bergenia ciliate using in vitro models
African Journal of Pharmacy and Pharmacology, 9 (20) pp: 547-552 (2015)
17. Zia Ul Haq Khan, Arif Ullah Khan, Pingyu Wan, Yongmei Chen, Dandan Kong, Shafiullah Khan & Kamran Tahir.
In vitro pharmacological screening of three newly synthesised pyrimidine derivatives
Natural Product Research 28, pp: 1-6 (2014)
18. Shafiullah Khan, Wang Zhao, Runguo Wang, Liqun Zhang*
Horizontoates A‒C: New cholinesterase inhibitors from Cotoneaster horizontalis.
Phytochemistry Letters 10, pp: 204-208 (2014)
19. Zia Ul Haq Khan, Yongmei Chen, Shafiullah Khan, Dandan Kong, Mo Heng Liang, Pingyu Wan, Xin Jin.
Electrochemical Initiation of Nucleophilic Substitution of Hydroquinone with 4, 6-Dimethylpyrimidine-2-thiol.
International Journal of Electrochemical Science 9, pp: 4665-4674 (2014)
20. Dilfaraz Khan, Masood Afzal, Farman Ali and Shafiullah khan*
New Cholinesterase Inhibitory Constituents from Lonicera quinquelocularis.
PLOS/ONE 9 (4), pp: 94952-94957 (2014)
21. Dilfaraz Khan, Masood Afzal, Simon Woodward and Shafiullah Khan*
Two new antioxidant Triterpenoids from Lonicera quinquelocularis.
Record of Natural Product 8 (2), pp: 121-127 (2014).
22. Zaher Shah, Farman Ali, Hidayat Ullah, Dilfaraz Khan, Shafiullah Khan & Irshad Ali.
Biological Screening and Chemical Constituents of Viburnum grandiflorum.
Journal of Chemical Society of Pakistan 36 (1), pp: 113-118 (2014)
23. Kamran Tahir, Sadia Nazir, Naijin Wu, Arifullah Khan, Qin Jing and Shafiullah Khan* Cholinesterase Inhibitory Assay and Antimicrobial Effect of Four Constituents of Lonicera quinquelocularis Against Gram Positive and Gram Negative Bacteria.
Global Journal of Pharmacology 8 (2) pp: 221-227 (2014).
24. Amjad Khan, Zia Ul Haq Khan, Pingyu Wan, Yongmei Chen, Don Kong, Mo Heng Liang, Karman Tahir, ArifUllah Khan, S Nazir and Shafiullah Khan*
In vitro potential antimicrobial activities of medicinal plants, Cirsium arvense and Cirsium japonicum.
African Journal of Plant Sciences Vol: 8 (2), pp: 84-91 (2014)
25. Fatima Syed, Raheela Taj, Nusrat Shaheen, Musarat Norin and Shafiullah Khan*
Latent natural product and their potential application as anti- infective agents.
African Journal of Pharmacy and Pharmacology Vol: 8 (4), pp: 100-105 (2014)
26. Sadia Nazir, Wang Zhao, Kamran Tahir, Qin jing and Shafiullah Khan*
In vitro Antimicrobial Activity of the Chemical Ingredients of Ranunculus hirtellus.
Global Journal of Pharmacology 8 (1), pp: 53-59 (2014)
27. Zia Ul Haq Khan, Shafiullah Khan*, Yongmei Chen, Sadaf Ul Hassan, Pingyu Wan.
Natural Products – New Antimicrobial Constituents Derived from Cerium arvense.
International Journal of Plant Research 4(1), pp: 5-10 (2014)
28. Dilfaraz Khan, Wang Zhao, Saeed Ahmad and Shafiullah Khan*
New antioxidant and cholinesterase inhibitory constituents from Lonicera quinquelocularis.
Journal of Medicinal Plant Research Vol: 8 (6), pp: 313-317 (2014)
29. Masood Afzal, Zhao Wang, Farman ali, Zhongshu Song, Russel Cox and Shafiullah Khan*
Preliminary phytochemical screening and antimicrobial activities of various fractions of Mallotus philippensis Muell.
Journal of Medicinal Plant Research Vol: 7 (41), pp: 3066-3070 (2013)
30. Sadia Nazir, Baoshan Li, Kamran Tahir, A. Khan, Zia Ul Haq Khan and Shafiullah Khan*
Antimicrobial activity of five constituents isolated from Ranunculus muricatus.
Journal of Medicinal Plant Research Vol: 7 (47), pp: 3438-3443 (2013)
31. Farman Ali, Masood Afzal, Shafiullah Khan and Irshad Ali.
Two new Cholinesterase inhibitors asiatoats A and B from Buddleja asiatica.
Journal of Asian Natural Product Research Vol: 15 (6) pp: 631-637 (2013)
32. Fatima Syed, Rifat Jahan, Aftab Ahmed and Shafiullah Khan*
In vitro antimicrobial activities of Glycyrrhiza glabra and Fagonia Arabica.
Journal of Medicinal Plants Research Vol:7 (10) pp:2265-2270 (2013)
33. Zia Ul Haq Khan, Shafiullah Khan, Yongmei Chen and Pingyu Wan.
In vitro antimicrobial activity of the chemical constituents of Cirsium arvense.
Journal of Medicinal Plants Research Vol:7 (25) pp:1894-1898 (2013)
34. Shafiullah Khan* and Fatima Syed (Review).
Bioactive constituents from Genus Otostegia. SARJ of Physical Science Vol:1 pp:15-25 (2012)
35. Jing Zheng, Cong Liu, Michael R. Sawaya, Balraju Vadla, Shafiullah Khan, R. J.Woods, David Eisenberg, Warren J. Goux & James S. Nowick*
Macrocyclic β-Sheet Peptides that Inhibit the Aggregation of a Tau-Protein-Derived Hexapeptide.
Journal of American Chemical Society 133, pp: 3144-3157 (2011)
36. Zia ul Haq Khan, Farman Ali, Shafiullah Khan & Irshad Ali.
Phytochemical study on the constituents from Cirsium arvense.
Mediterranean Journal of Chemistry, Vol.2, pp: 64-69 (2011)
37. Shafiullah Khan, N. Riaz, A.U.Rehman, Nighat Afza, L.Iqbal, M. Lateef & A. Malik.
A new lignan rhamnoside, racemiside has been isolated from Cotoneaster racemiflora.
Journal of Asian Natural Product Research Vol. 11, No.1, 44- 48 (2009)
38. Shafiullah Khan, S. Yasmeen, N. Afza, & A. Malik.
Cotonoate A and B, New aromatic esters from Cotoneaster racemiflora.
Journal of Z- Natureforsch 63 b, pp: 1219-1222, (2008)
39. Shafiullah Khan, A.Rehman, N.Riaz, N.Afza, A.Malik.
Phytochemical investigation on Cotoneaster racemiflora.
Journal of Chemical Society Pakistan 29(6), 620-623 (2007)
40. N.Riaz, S.A.Nawaz, N.Mukhtar, A.Malik, N.Afza, S.Ali, Shafiullah Khan, Pir Muhammad & M.I.Chaudhary.
Isolation and enzyme-inhibition studies of the chemical constituents from ajuga bracteosa.
Chemistry & Biodiversity Vol.4, pp: 72-83 (2007)
41. I. Ahmed, H.Anis, I. Fatima, A. Malik, Shafiullah Khan, N.Afza, R.Bukshs, M.A.Lodhi & M.I.Chaudhary.
Two new protease- inhibiting Glycosphing Olipids from Buddleja Crispa.
Chemistry & Biodiversity Vol. 4 (5), pp: 917-924 (2007)
REFERENCES
Dr. James S Nowick
Professor of Chemistry
Department of Chemistry 4126 Natural Sciences 1
University of California Irvine, CA 92697-2025, U.S.A
Phone: (949) 824-6091
FAX: (949) 824-9920
E-mail: jsnowick@uci.edu
Dr. Liqun Zhang
Professor and Dean
College of Material Science, Center of Advance Elastomer Material, Beijing University of Chemical Technology, Beijing, China.
Tel Office: +86- 10-6443-4860. Fax: +86-10-6443-3964.
Email: zhanglq@mail.buct.edu.cn
Prof. Dr. Abdul Malik S.I.
International Center for Chemical and Biological Sciences
H. E. J. Research Institute of chemistryUniversity of Karachi,
Karachi-75270Pakistan.
E-mail: abdul.malik@iccs.edu
Tel: +92-21-111-222-292 Ext. 139